Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in maladaptive renal repair in mice and humans.Using single-cell transcriptomic and mouse genetic approaches, Hutch we show that proximal tubular (PT) cells develop a molecularly distinct, pro-inflammator

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Investigating Geomorphic Change Using a Structure from Motion Elevation Model Created from Historical Aerial Imagery: A Case Study in Northern Lake Michigan, USA

South Manitou Island, part of Sleeping Bear Dunes National Lakeshore in northern Lake Michigan, is a post-glacial lacustrine landscape with substantial geomorphic changes including landslides, shoreline and bluff retreat, and sand dune movement.These changes involve interrelated processes, and are influenced to different extents by lake level, clim

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